Caffeine is a stimulant that is used to stay awake and it gives mental alertness from fatigue. This is used as an adjunct for pain relief and also as energy accelerates. Caffeine is a non-prescription drug easily available as over the counter medication and comes in combination to acquire relief from headache and pain. Caffeine increases the mental alertness by offering the required energy for exercise training and weight loss. Caffeine cannot be considered as a mere stimulant as it reaches deep into muscles and provides power that is long lasting. Caffeine taken before any work out is also great as it fights the fatigue and keeps the person ready for the workout. Dieters also find caffeine as the solution as they feel sluggish. This is a no-calorie stimulant and does its job effectively and quickly. Caffeine anhydrous is found even in one or two coffee cups. However, this limitation is recommended as excess caffeine may result in irritability, rapid heart beat, nervousness and sleeplessness.

Diiodotyrosine, used by the thyroid hormones T4 and T3, Diiodotyrosine may help the thyroid gland to maintain proper function and help preserve lean muscle and supports the thyroid without suppressing TSH levels.

Evodiamine, an alkaloid extract from the Evodiae Fructus plant is known as Evodiamine. It has been referred to as a “hot nature” herb in Chinese literature and medicine. Based on animal studies, Evodiamine increases the natural fat burning rate and stimulates vanilloids for reduction of fat intake. It increases body temperature, influences the adrenal glands to secrete catecholamines and also affects the metabolism of certain drugs. Since it acts like a thermogenic and increases the overall temperature, more fat and calories are burnt due to its intake. This alkaloidal compound has anti obesity effects due to UCP1 (uncoupling protein 1) thermogenesis. In part, evodiamine can prevent diet induced obesity from developing further. It is available in the form of supplement or through Evodiae Fructus plant.

Green Tea Extract- Camellia sinensis, or more commonly the tea plant is a genus of flowering plants which is generally being used to produce tea, including green tea, oolong, black tea, white tea and pu-erh tea, also called Bolay tea. The different oxidation process makes the final difference. Tea plants can grow out into a tree, but are generally pruned to allow for easy hand picking. While camellia sinensis is being cultivated all around the globe in tropical and subtropical regions, this South and Southeast Asian native is most popular when imported from India and China. Medical uses of tea stem from the traditional Chinese medicine, where it was used as a bronchodilator and to treat angina pectoris, coronary artery disease and peripheral vascular diseases. Green tea extract is used as appetite suppressant and thermogenesis increasing agent.

Iodotyrosone, which is a form of tyrosine with iodine added.

L-Tyrosine, a non-essential amino acid that is used to build protein. It is a precursor dopamine, as well as a precursor to norepinephrine and epinephrine. The body makes L-Tyrosine from the amino acid phenylalanine. Since L-Tyrosine is a precursor of Dopamine, it may raise mental alertness, making it of great use in exercise programs.

Naringin, which is a citrus flavanoid that is found in grapefruit. Naringin is commonly used in energy supplements as it may extend the duration of the effects of caffeine.

Octopamine is a biogenic substance which is containing an amine group, apparently related to noradrenaline, which is a catecholamine functioning as both, neurotransmitter and a hormone. Similar to norepinephrine, which is another name for noradrenaline, octopamine may act as a stress hormone, triggering increased heart rate, energy consumption and blood flow, even the blood pressure. One side effect of octopamine is apparently the release of fat from the adipocytes, which are the fat cells where excess energy is being stored. This side effect prompted the use of octopamine as a dietary supplement aimed at weight loss, but used in combination with other stimulants. Octopamine has been discovered in the middle of the twentieth century, but the use as a fat removal agent is very recent.

Synephrine is an adrenergic amines and stimulant with beta-3 receptors. It functions to increase metabolic rate with no effect to heart rate or blood pressure. Synephrine releases adrenaline and noradrenalin in the adipose tissue and the liver. Stimulation of the beta-3 receptor sites to educe the breakdown of fat. It can be added to the group of stimulants, to which belong such supplements as caffeine or ephedrine. Can be used to boost energy, suppress appetite and enhance metabolic rate to burn more calories and increased the energy, but it does not cause so undesired negative cardiovascular effects. Its active ingredients include gelatin, cellulose, and silica and magnesium strearate. Its weight loss abilities are associated with citrus aurantium (synephrine) supplements which give it the stimulant like effects of the alkaloids.

Yerba Matte- Described as an ancient drink of friendship derived from a small shrub. It is sometimes spelled as yerba mate and people drink it in order to gain energy producing properties without consuming caffeine as they would in normal tea or coffee. People believe that yerba mate is a appetite suppressant, clears the mind as well as relieving allergies, improving sleep patterns and lifting the mood, that is why it is used in Thermonex EF. It is advertised as an aid to weight loss, a fortifier of the immune system, a colon cleanser and even as a means of extending life. It is prepared as an infusion, with twigs and leaves immersed in boiling water in order to produce a tisane. Traditionally it is made in a vessel which is then shared among friends.