Caffeine, is a naturally produced medicine from the seeds and leaves of many plants. It is also produced unnaturally to add to certain foods. Caffeine is termed as a medicine because it arouses the central nervous system, causing enhanced alertness. Caffeine gives most people a short-term energy boost and bump up mood. Caffeine is present in tea, many soft drinks, coffee, chocolate, and pain relievers and other over-the-counter medicines. Caffeine tastes very bitter in its natural form. However, most caffeinated drinks undergo processing to cover-up the bitter taste. You may feel caffeine’s effects for up to 6 hours though it is not stored in the body.

Citrus Aurantium, More commonly called "bitter orange", which is taken from unripe oranges. Research shows that citrus aurantium can increase the metabolic rate without affecting heart rate or blood pressure, breaks down fat, burns calories and may act as an appetite suppressant.

Ephedra Viridis (Stems).

Guggulsterone is a plant sterol found in the resin of the guggul plant, Commiphora mukul. It acts as an antagonist of the farnesoid X receptor, which was earlier believed to result in decreased cholesterol synthesis in the liver.

Gymnema Sylvestre is an herb stemming from southern and central India where it has been used for nearly 2000 years as a naturopathic treatment for diabetes.

Hoodia Gordonii grows in Namibia and South Africa naturally. It is a leafless spiny plant useful for medicinal purposes. These flowers are pollinated by flies mainly as they smell identical to rotten meat. Hoodia is known long by indigenous population and is infrequently used for treating small infections and indigestion. This is used to suppress appetite during long hunting trips such as Kalahari Desert that interests more tourists. Hoodia Gordonii was prominent for it appetite suppressing effect and hence was collaborated with Pfizer, a pharmaceutical company to deal with obesity. However, it was stopped as it is stated to have indications of effects on liver. Hoodia Gordonii is wild harvested by individuals as well as by few companies that are granted license. However, there is no evidence of Hoodia working in humans as appetite suppressant. Due to the lack of clarity and fear of breaking down of liver, it is not recommended for obesity.

L-Carnitine is a naturally occurring nutrient in the body that helps the body turn fats into energy. It is primarily produced in the liver and kidneys, and is stored in the muscles of the heart, brain, skeleton, and sperm. L-Carnitine is commonly used in supplements used by body builders. It helps increase and boosts the process of burning of fat in the body that gives energy, promotes a healthy cardiovascular system, proper circulation of blood and a healthy liver. It also helps suppress and reduce the appetite. It also helps those with chronic fatigue syndrome, increasing the focus, energy level, and reduces exhaustion.

Magnesium is the chemical element found in the periodic table with the atomic number 12. This alkaline earth metal is one of ten most common elements in the known universe and also very prominently present in the human body. It manipulates polyphosphate compounds, most prominently the DNA, RNA and the ATP. Numerous enzymes rely on magnesium ions to function properly. Most common application of magnesium in medicine may be the addition to antacids and laxatives. This metal is not found as a free element naturally on Earth, generally the metal is obtained through electrolysis of magnesium salts. The most common deficiency in the United States with staggering two thirds of the population is the magnesium deficiency. Magnesium can be obtained through vegetables, tea, cocoa, cereals, coffee, nuts and spices.

Silica is silicon dioxide, a trace mineral found in bones, teeth, skin, eyes, glands and organs. It also helps keep skin elastic. Silica works with calcium to maintain bone strength.

White Willow Bark, or Salix alba, is a willow commonly found in Europe and adjacent parts of western and central Asia. The bark of the White Willow has been used for centuries against fevers and to ease pains and aches. Already Hippocrates wrote about the White Willow bark powder two thousand five hundred years ago. The active ingredient of the White Willow bark is called salicin, a relative to aspirin and chemical derivative of the salicylic acid. When ingested, salicin is converted to salicylic acid, a beta hydroxy acid. As a nutritional supplement, White Willow products are being propagated as weight loss additives, whereby the scientific community has yet to provide any corroboration to this allegation. Besides the well known anti inflammatory characteristics, any other uses have not been approved by the FDA.