Caffeine may be the most popular legal addictive stimulant that is available to mankind. Besides coffee, tea, guarana and kola nut have excess amount of this xanthine alkaloid, which is actually acting as a psychoactive drug. In several plants, caffeine is an effective insect repellant, but this trimethylxanthine is deemed by the Food and Drug Administration as generally safe food substance. It is an antagonist of adenosine receptors. The effect of caffeine is individual and may more or less increase the ability to perform physical and mental labor. It reduces the effects of fatigue and may in long term help predominantly men reduce the risk of developing Parkinson’s disease. It has also been observed that caffeine has nootropic effects, furthermore, regular consumption of caffeine may significantly reduce the risk of heart diseases.

Citrus Aurantium, More commonly called "bitter orange", which is taken from unripe oranges. Research shows that citrus aurantium can increase the metabolic rate without affecting heart rate or blood pressure, breaks down fat, burns calories and may act as an appetite suppressant.

Evodia Rutaecarpa is used to prevent digestive disorders and has anti-inflammatory characteristics. It also keeps the blood thin so that the nutrients pass through the body with ease.

Glucuronolactone is a naturally occurring metabolite present in the body. This substance hastens the riddance of exogenic and endogenic noxal – a harmful substance and thereby detoxifies the body and improves the functioning of the liver. Due to its ability to reduce viral and bacterial beta-glucuronidase, it is used for curing typhoid patients. It is widely used in energy drink to fight fatigue or to improve workout performance. Glucuronolactone is an active ingredient that helps the brain retain memory, encourages elatedness and reduces depression and sleepiness. Glucuronolactone supplement benefit those who wish to boost their level of energy. It is present in stimulant drinks like Viper Extreme and Red Bull. To increase energy glucuronolactone must be taken in doses of 100 – 200 milligrams. It works the best when combined with taurine and caffeine.

L-Taurine , a semi-essential amino acid found in the heart muscle, central nervous system, white blood cells, and skeletal muscle, may not be as popular as other types of aminos such as glutamine, but is extremely crucial. It is also vital for metabolism. While taurine is made in adults’ bodies, newborns cannot make it. If the body fails to produce it in sufficient quantities, it is possible to correct this deficiency by using L-Taurine supplements. You are likely to get enough taurine if you are a meat eater since it is found in abundance in eggs, meats, fish proteins, and dairy products. Generally, vegetarians and women of all ages are at a greater risk of developing a L-Taurine deficiency. It is possible to treat depression, low sperm count, low sperm motility, high blood pressure, and cirrhosis using this supplement.

L-Tyrosine is an amino acid that is nonessential. It is synthesized from the body from phenylalanine which is also an amino acid. L-Tyrosine has the power to have an effect on the neurotransmitters and this affects various health conditions including depression, mood disorders and Parkinson’s disease. Many such studies have proved that L-Tyrosine helps people having depression. It acts as a precursor and eases the effects of psychosocial, environmental and physical stress. L-Tyrosine turns into melanin by the skin cells and the dark pigment prevents the ultraviolet light from affecting. The thyroid hormones playing a significant role in the process of the body also contain tyrosine. L-Tyrosine is commonly found in all the dairy products, fish, oats, wheat, meat and also in all other protein containing foods. This is also found to be beneficial for people trying to withdraw alcohol. L-Tyrosine has not exhibited severe side effects, yet taking it should be recommended by doctors.

Niacin is a vitamin that wards against pellagra, a disease characterized by a vitamin B3 deficiency. Niacin is made from pyridine and is often called vitamin B3 or nicotinamide, because they all three have similar formulas. Niacin and nicotinamide are comparable in make up, but only niacin works to lower cholesterol levels. The restoration of DNA is also known to be a positive side effect of taking niacin. A fairly large number of individuals, particularly those in third world countries or those suffering from alcoholism, have been shown to be lacking in niacin. Niacin is often taken as a supplement by those with high cholesterol levels, as it has been proven to lower “bad” cholesterol and raise “good” cholesterol.

Octopamine, which is a trace amine, recently believed to be a lipotropic for fat loss. Octopamine has low oral bioavailability and is readily broken down by MAOI, as well as metabolized by the gut wall, which may mean it would not work well when taken orally, but more research is needed to prove its positive or negative effects.

Pantothenic Acid, also called vitamin B5, which is a water-soluble vitamin required by the human body. Pantothenic acid is needed to form coenzyme-A (CoA), and is vital in the metabolism and synthesis of carbohydrates, proteins, and fats.

Rhodiola , popularly known as the “golden root” in Russia has been considered an effective treatment for stress and depression. This adaptogenic herb enhances resistance without changing the normal biological function of the body. Rhodiola is found in Asia and Europe’s artic areas at high altitudes. Scandinavian and Russian countries have been using its roots to cure poor attention span and fatigue for centuries. Rhodiola rosea is also effective in improving mood by enhancing mental and physical performance. There are several compounds in Rhodiola rosea which makes it so effective. It includes rosavins along with active components like tyrosol and rhodioloside. This supplement is available in the form of tablet or capsules that can be taken once or twice on a daily basis. You can also increase the dosage if needed.

Salvia Sclarea

Thiamine is a water-soluble vitamin with no known toxic effects if taken with other members of the vitamin B complex. Thiamine is essential to a strong appetite and to enable the body to use sugars and other carbohydrates.

Vinpocetine is available in capsule form. Vinpocetine has certain properties which helps move the right amount of blood to the brain from the body. It also enhances certain components of the body. The advantage of consuming this natural substance is it helps oxygen and blood flow to the brain, this helps overcome obstacles which form in the eyes. Many diagnosed with eye disorders that have an impact on the overall eyesight have successfully recovered after using this natural extract. It eliminates cognitive impairments which cause low metabolism, dangerous clots and memory loss. Ingestion of Vinpocetine seems to have a positive correlation with the healing of Tinnitus – the buzzing or ringing sensation in the ear, which is mainly caused due to the disruption of natural blood flow through the entire body. It greatly helps optimize your overall health conditions. Vinpocetine mainly contains the extract from the popular periwinkle plant.

Vitamin B12, also known as cobalamin, which is naturally found in foods such as fish, milk and milk products, eggs, meat and poultry. Vitamin B12 is important for good health, necessary for the proper digestion and absorption of foods and for normal metabolism of carbohydrates, and fat. It helps maintain healthy nerve cells and red blood cells and is needed to make DNA. Vitamin B12 is bound to the protein in food. Hydrochloric acid in the stomach releases B12 from protein during digestion. Unlike other water-soluble nutrients, vitamin B12 is stored in the liver, kidney, and other body tissues. It can take several years before signs of the deficiency appear due to poor dietary intake. Vitamin B12 functions as a "methyl donor." A methyl donor is a compound that carries and donates methyl groups to other molecules, including cell membrane components and neurotransmitters. As a methyl donor vitamin B12 is involved in homocysteine metabolism and plays a critical role in proper energy metabolism, immune function, and nerve function. Therefore, vitamin B12 is clearly an added benefit for anyone wanting to lose weight, as without it, metabolism is not at its peak potential.

Vitamin B6, which active form pyridoxal phosphate or otherwise known as PLP and pyridoxal-5’-phosphate, is a prosthetic group of tightly bound cofactors responsible for many reactions within the amino acid metabolism and the manipulation of the enzymatic reaction behind the release of glucose from glycogen. Vitamin B6 generally comprises three organic compounds, pyridoxine, pyridoxal and pyridoxamine, all of them heterocyclic organic compounds that are converted in the human body to the active pyridoxal phosphate form. There are three reactions attributed to PLP, namely transamination, alpha elimination and beta elimination. Over one hundred and forty enzyme activities depend on pyridoxal phosphate, neurotransmitter and histamine synthesis, synthesis and function of hemoglobin, and gene expression. As a cofactor, PLP is active in amino acid metabolism, glucogenesis and lipid metabolism.

Yohimbine HCL raises body temperatures. it increases the flow of blood to the genital area and increases the sex drive in men but also women have reported similar effects.