Caffeine is the most widely used legal stimulant of the central nervous system and is also used in Covaxil Laboratories Estrin-D, with characteristics that have been described as restoration of alertness and removing from drowsiness. Coffee, Tea, many soft drinks and energy drinks as well as nutrition supplements have this ingredient, which is a psychoactive substance, a xanthine alkaloid that can act as a adenosine receptor antagonist, as well as a phosphodiesterase inhibitor. Although regular use of caffeine seems to have nootropic effects, enhancing cognitive abilities, it also is known to provide long term effects on the nervous and cardiovascular system, like in one study it was proven that people with normal to low blood pressure have the possibility of developing a heart disease significantly reduced, as well as the chance of getting the Parkinson’s disease.

Cocoa Concentrates is the concentrate of Theobroma cacao. It is cultivated for its seeds which are present in its pod shaped fruits. The extracts from its seeds have a number of health benefits. They are also used to make chocolate. Studies show that Cocoa extracts contain a high level of flavonoids, specifically epicatechin, which may have beneficial cardiovascular effects on health. The ingestion of flavonol-rich cocoa is associated with acute elevation of circulating nitric oxide, enhanced flow-mediated vasodilatation, and augmented microcirculation. Researchers also found that consumption of Cocoa can reduce risk of cancer and can reduce elevated blood pressure.

Damiana is a shrub belonging to the family of Turneraceae. Even though it is a small shrub, it produces aromatic, small flowers. It is generally found in the regions of South America, Caribbean, Mexico and Central America. It is also a fruit bearing shrub. The flowers generally blossom in late summer on the damiana shrub. Then the fruits follow. The fruit it bears is quite similar in taste to figs. It emits a smell which is quite similar to the odor of chamomile. The oils present in the shrub are reason behind this odor. It is said to have aphrodisiac properties. Natives of south and Central America use the leaves to make tea. In Mexico, the tea made with damiana leaves is generally drunk with sugar so as to increase the love making ability.

DHEA, short for dehydroepiandrosterone, is a steroid which is found in abundance in humans. DHEA seems to be involved in a variety of biological effects in mammals, produced by the adrenal glands, but also being synthesized in the brain, it manipulates the androgen receptor indirectly and directly, if indirectly then through metabolites. Considered a neurosteroid, it can be also viewed as a prohormone for the gonadal steroids. DHEA is produced by means of two cytochrome P450 enzymes from cholesterol. As a supplement it continues to be of widespread importance and popularity, particularly within the body building communities. Apparently the use of DHEA is helping individuals lose weight, burn fat and bulk up on muscle mass. Other purported effects include promoting of the immune system, healthy blood sugar levels and overall well being.

Ginger Root is a dietary supplement that is not only used as a spice but has had a positive effect on some types of arthritis and raynauds disease.

Ginseng Extract is an extract taken from the slow growing perennial plants with the fleshy roots. These plants are found mostly in China, Korea and eastern Siberia. China, Japan and Korea have been using this extract for centuries to cure various kinds of illnesses. Ginseng extract helps in enhancing vitality along with helping in curing psychiatric and neurological conditions. There are a total of species that fall under the category of these root plants. But only a few are used widely. Asian ginseng, American ginseng and Siberian ginseng are the few that have been used commonly for a long period of time. They all are used for different purposes. Asian ginseng is used to raise the body temperature and also works as stimulant. Whereas, American ginseng increases the body temperature very less as compared to the Asian ginseng. It is also less stimulating than the Asian ginseng.

Green Tea Extract is very popular with the health conscious community, mainly because of the broad antioxidant features, which are provided by the green tea catechins. It is a very popular nutritional supplement, much more popular than regular green tea, because several green tea extract products have no caffeine. Caffeine is actually contained in larger quantities in green tea than in coffee. Besides the already mentioned catechins, further polyphenols are included in the Asian tea favorite. Green tea furthermore contains carotenoids, ascorbic acid – more commonly known as Vitamin C, Minerals and tocopherols. While there are many proven qualities of green tea extracts, some lesser researched effects have been observed, like reduction of LDL cholesterol, increasing the levels of norepinephrine, weight loss and additional antioxidant qualities.

Guarana is not only a dietary supplement but also an energy booster as well as it has a high concentration of caffeine.

Kola Nut has a euphoric and stimulating effect on the heart and central nervous system and produces a heightened state of euphoria and well-being.

Magnesium, which is a mineral used by the body to help maintain muscles, bones, and nerves. Magnesium is also needed for energy metabolism and protein synthesis.

Schisandra

Vitamin B6, which active form pyridoxal phosphate or otherwise known as PLP and pyridoxal-5’-phosphate, is a prosthetic group of tightly bound cofactors responsible for many reactions within the amino acid metabolism and the manipulation of the enzymatic reaction behind the release of glucose from glycogen. Vitamin B6 generally comprises three organic compounds, pyridoxine, pyridoxal and pyridoxamine, all of them heterocyclic organic compounds that are converted in the human body to the active pyridoxal phosphate form. There are three reactions attributed to PLP, namely transamination, alpha elimination and beta elimination. Over one hundred and forty enzyme activities depend on pyridoxal phosphate, neurotransmitter and histamine synthesis, synthesis and function of hemoglobin, and gene expression. As a cofactor, PLP is active in amino acid metabolism, glucogenesis and lipid metabolism.

Yerba Matte is believed to possess cancer-fighting properties and has shown to have a relaxing effect on muscle tissues and a stimulating effect on heart tissues.