Caffeine is the most widely used legal stimulant of the central nervous system and is also used in Covaxil Laboratories Estrin-D, with characteristics that have been described as restoration of alertness and removing from drowsiness. Coffee, Tea, many soft drinks and energy drinks as well as nutrition supplements have this ingredient, which is a psychoactive substance, a xanthine alkaloid that can act as a adenosine receptor antagonist, as well as a phosphodiesterase inhibitor. Although regular use of caffeine seems to have nootropic effects, enhancing cognitive abilities, it also is known to provide long term effects on the nervous and cardiovascular system, like in one study it was proven that people with normal to low blood pressure have the possibility of developing a heart disease significantly reduced, as well as the chance of getting the Parkinson’s disease.

Cocoa Concentrates is the concentrate of Theobroma cacao. It is cultivated for its seeds which are present in its pod shaped fruits. The extracts from its seeds have a number of health benefits. They are also used to make chocolate. Studies show that Cocoa extracts contain a high level of flavonoids, specifically epicatechin, which may have beneficial cardiovascular effects on health. The ingestion of flavonol-rich cocoa is associated with acute elevation of circulating nitric oxide, enhanced flow-mediated vasodilatation, and augmented microcirculation. Researchers also found that consumption of Cocoa can reduce risk of cancer and can reduce elevated blood pressure.

Damiana is a shrub belonging to the family of Turneraceae. Even though it is a small shrub, it produces aromatic, small flowers. It is generally found in the regions of South America, Caribbean, Mexico and Central America. It is also a fruit bearing shrub. The flowers generally blossom in late summer on the damiana shrub. Then the fruits follow. The fruit it bears is quite similar in taste to figs. It emits a smell which is quite similar to the odor of chamomile. The oils present in the shrub are reason behind this odor. It is said to have aphrodisiac properties. Natives of south and Central America use the leaves to make tea. In Mexico, the tea made with damiana leaves is generally drunk with sugar so as to increase the love making ability.

DHEA is an endogenous steroid. It is the most abundant steroid in human beings. It acts on the androgen receptor directly and through its metabolites (androstenediol and androstenedione). These metabolities can undergo further conversion to produce the androgen testosterone and the estrogens estrone and estradiol. It is produced synthetically and used as a supplement because studies show that it can decrease cholesterol and other serum lipids. DHEA is used by muscle builders and athletes because it is believed to increase strength, lean body mass and testosterone levels, however, some researchers don’t agree with these claims.

Ginger Root is a dietary supplement that is not only used as a spice but has had a positive effect on some types of arthritis and raynauds disease.

Ginseng Extract is an extract taken from the slow growing perennial plants with the fleshy roots. These plants are found mostly in China, Korea and eastern Siberia. China, Japan and Korea have been using this extract for centuries to cure various kinds of illnesses. Ginseng extract helps in enhancing vitality along with helping in curing psychiatric and neurological conditions. There are a total of species that fall under the category of these root plants. But only a few are used widely. Asian ginseng, American ginseng and Siberian ginseng are the few that have been used commonly for a long period of time. They all are used for different purposes. Asian ginseng is used to raise the body temperature and also works as stimulant. Whereas, American ginseng increases the body temperature very less as compared to the Asian ginseng. It is also less stimulating than the Asian ginseng.

Green Tea Extract is very popular with the health conscious community, mainly because of the broad antioxidant features, which are provided by the green tea catechins. It is a very popular nutritional supplement, much more popular than regular green tea, because several green tea extract products have no caffeine. Caffeine is actually contained in larger quantities in green tea than in coffee. Besides the already mentioned catechins, further polyphenols are included in the Asian tea favorite. Green tea furthermore contains carotenoids, ascorbic acid – more commonly known as Vitamin C, Minerals and tocopherols. While there are many proven qualities of green tea extracts, some lesser researched effects have been observed, like reduction of LDL cholesterol, increasing the levels of norepinephrine, weight loss and additional antioxidant qualities.

Guarana contains a significant amount of guaranine, a substance that is similar to caffeine found in coffee beans. It helps stimulate the adrenal glands and increase the production and release of hormones such as epinephrine, norepinephrine (adrenaline), and dopamine. This helps the metabolism of the body that enhances fat loss, and increases energy and endurance. It helps the body burn the fats to be used for energy. It aids in fighting stress, weakness and fatigue. As a stimulant, it also improves mental alertness, clarity, focus, concentration, and memory retention. Guarana also also improves the libido or sex drive in both men and women. Guarana also contains tannins that help prevent diarrhea and soothes the digestive system.

Kola Nut has a euphoric and stimulating effect on the heart and central nervous system and produces a heightened state of euphoria and well-being.

Magnesium is the chemical element found in the periodic table with the atomic number 12. This alkaline earth metal is one of ten most common elements in the known universe and also very prominently present in the human body. It manipulates polyphosphate compounds, most prominently the DNA, RNA and the ATP. Numerous enzymes rely on magnesium ions to function properly. Most common application of magnesium in medicine may be the addition to antacids and laxatives. This metal is not found as a free element naturally on Earth, generally the metal is obtained through electrolysis of magnesium salts. The most common deficiency in the United States with staggering two thirds of the population is the magnesium deficiency. Magnesium can be obtained through vegetables, tea, cocoa, cereals, coffee, nuts and spices.

Schisandra

Vitamin B6 is soluble in water and is essential for good health. Our nervous system is dependent on this vitamin to function properly. It keeps the thymus, lymph nodes and the spleen that make white blood cells healthy, through cellular growth and protein metabolism. A deficiency in this vitamin can lead to a weakened ability to fight infections and will weaken the immune system. Vitamin B6 helps in the formation of Hemoglobin which increases the oxygen that is carried to the tissues. A deficiency can cause a type of anemia. Vitamin B6 helps to convert carbohydrates and other nutrients into glucose which maintains the sugar levels in our blood stream. Vitamin B6 is available in meat, fish, fortified cereals, poultry, some fruits and vegetables.

Yerba Matte, actually yerba maté, as it is called in Brazil, or Ilex paraguariensis in Latin, is a small tree or a shrub which can grow to fifteen meters. It is found naturally in South America, mainly in south of Brazil, Argentina, Paraguay, Uruguay and Chile. Foliage is evergreen, and the flowers are rather small, additionally there is a smallish fruit of red color. A tea like brewing in warm water, not boiling, is a popular drink in the native area, similar social gathering is common, akin to tea time practice in the United Kingdom. Yerba matte has several xanthines alkaloids which are related to caffeine, but although chemically identical to caffeine the mate xanthine cocktail provides different results, for instance it relaxes smooth muscle tissue and stimulates heart tissue. Yerba Matte is a potent ingredient in Covaxil Laboratories Estrin-D.