Bioperine is a convenient and concentrated form of black pepper’s ingredient called piperine. Bioperine enhances bioavailability and absorption. Bioperine is a safe and pure nutritional piperine supplement. This is an alkaloid that is available from the fruits. Piperine is responsible for the ability of pepper to enhance the nutrients bioavailability. 95% piperine is present in Bioperine. Black pepper was popular as it was the most desired spice. The black pepper was useful in ayurvedic medicine as it increased the food digestibility. The pepper consumption shows positive indication by generating internal heat. The nutritional status is based on a person and his eating style. Bioperine enhances the heat production in the body and this result in food digestion and eventually the energy is used. Bioperine facilitates the bioavailability of nutrients in a broad range. Bioperine is considered to be a thermogenic local agent as it increases the thermogenic reactions. Bioperine is an apposite nutritional supplement identical to pepper that is to food.

Citric Acid ~

Cyclic Adenosine Monophosphate 3'-5'-cyclic adenosine monophosphate or Cyclic Adenosine Monophosphate, a second messenger that mediates the action of several eptide or amine hormones, is abbreviated as cyclic AMP or cAMP. cAMP is thus vital for varied biological processes and used for intracellular signal transduction in various organisms. This major communicator is a result of the action of the enzyme adenyl cyclase on ATP. As such, cyclic AMP performs many physiological functions and is also responsible for increasing blood glucose levels. Adrenaline that enhances blood sugar levels in the body is able to do so by stimulating cAMP production. Cyclic AMP plays an important role in the following: urine regulation synthesis of flagellar proteins in bacteria hormone release sensory and nerve processes Apart from these functions, it also helps in breakdown of lipids in some organisms to produce energy in the absence of sufficient glucose.

Di-Sodium Phosphate is a Sodium salt with a phosphoric base. It is soluble in water and is used commercially to keep powdered products from forming cakes. It is also used as a stabilizer and buffering agent in various foods and as an emulsifying agent in manufacturing pasteurized processed cheese. It is added to powdered milk to help keep it from clumping. Prolonged inhalation and ingestion of Disodium Phosphate, however, does have its effects. Inhalation over a long period of time can bring about disorders of the respiratory tract, while ingesting the same can cause lethargy, vomiting, heart diseases and neurological disorders. Contact with the skin and eyes can cause irritation, inflammation and pain. It may also cause an increased aggravation of pre existing health problems.

Dioscorea Villosa extract is a medicinal herb commonly knows as the wild yam. It has medicinal properties that help in curing the pain caused during menstrual cycle, stomach cramps, and discomfort from gallstones and rheumatoid arthritis. It has been used fro centuries by the Native Americans. It is also used by herbalists for female and childbirth related problems. Along with herbal medicine, this plant is of great use in the modern medicine as well. It is because of this plant that birth control pills are so commonly and easily available. Its steroid like property explains the vast usage of this plant for medicinal purposes. But consumption of this extract may also lead to a number of side effects. Vomiting, diarrhea, nausea and headache are some of the most common side effects of dioscorea villosa extract.

Evodiamine is a chemical that is extracted from a particular species of plants that has been shown to reduce overall fat intake.

Glabra, commonly known as licorice, is a root used to extract a sweet flavor from. Licorice is a plant belonging to the legume family, like peas and beans. It takes two to three years after planting for licorice to be harvested in autumn. It requires deep, fertile, well drained soil with a lot of sun to be able to grow. The extract from licorice is produced by boiling the roots with water and then evaporating all the water. This extract is then sold both in the form of solid and liquid. Glabra consists of a sweetener called glycyrrhizin which is many times sweeter than sucrose. It is used in lot cough syrups and in ayurvedic medicine. Candies made from licorice roots are famous all over the world. Hence it is in many pharmaceutical and confectionery products.

Guggulsterone- Commiphora wightii, or the so called Guggul tree is a flowering shrub or rather a small tree which can grow up to a size of 4 meters. Once very common in India, it is now there listed as endangered, but not in northern Africa or elsewhere in central Asia. It was very popular in the Indian Ayurvedic medicine, but also currently in the western medicine for treating of heart problems. The hydrocarbon secretion of Guggul contains a plant sterol, guggulsterone, which in the human body seems to act as an antagonist to the farnesoid X receptor. Furthermore, guggulsterone is active in increasing the natural thyroid production. This in turn stimulates the metabolism and may raise the body temperature, burning stored excess fat.

Horsetail Herb- Horsetail is a perennial herb that grows in sandy soil in the North America continent, Asia and Europe. Horsetail plants contain ancient lineage and are widely used in various roles. In the middle ages, the clumps of horsetail were employed as scouring pads that facilitates in iron cookware and hard pewter dishes cleaning. The horsetail has silicon content at highest levels and is significant in binding protein molecules as well as other connective tissues present in the human body. The horsetail properties as per clinical studies in Europe state that fractured or broken bones can be healed quicker if the patients take horsetail supplements. Horsetail reduces osteoporosis incidences and has health benefits linked. Athletes suffering from dislocated joints, sprains, torn ligament injuries can take advantage of getting cured by supplementing it with horsetail herb in their diet. The horsetail dosages are three tablets every day until it is completely healed. Bleeding problems can also be stopped if tea is consumed with this herb and similarly urinary problems can as well be treated.

L-Tyrosine is an amino acid that is nonessential. It is synthesized from the body from phenylalanine which is also an amino acid. L-Tyrosine has the power to have an effect on the neurotransmitters and this affects various health conditions including depression, mood disorders and Parkinson’s disease. Many such studies have proved that L-Tyrosine helps people having depression. It acts as a precursor and eases the effects of psychosocial, environmental and physical stress. L-Tyrosine turns into melanin by the skin cells and the dark pigment prevents the ultraviolet light from affecting. The thyroid hormones playing a significant role in the process of the body also contain tyrosine. L-Tyrosine is commonly found in all the dairy products, fish, oats, wheat, meat and also in all other protein containing foods. This is also found to be beneficial for people trying to withdraw alcohol. L-Tyrosine has not exhibited severe side effects, yet taking it should be recommended by doctors.

Octopamine is related to noradrenaline. Octopamine was discovered by Vittorio Erspamer, an Italian scientist in 1948. Octopamine has a significant role in mollusks and is the central nervous system in snail. Octopamine also has a vital role in memory and learning in the fruit fly and honey bee. Octopamine is also useful for the firefly in releasing the light production. Octopamine mobilizes releasing fat in mammals and this has developed into promotion as a slimming aid on the internet. However, there is no apparent evidence about Octopamine facilitating weight loss. Octopamine also significantly increases the blood pressure in combination with stimulants such as weight loss supplements. This is extensively used in energy demanding insects such as spiders, lobsters, crabs and crayfish as their behaviors also include egg-laying, jumping and flying. Among vertebrates, Octopamine substitutes norepinephrine and as well exhibits common side effects. Octopamine is sited in the locust jump such that it modulates the muscle activity allowing the leg muscles to contract effectively.

Phosphatidylcholine is a key phospholipid constituent of cell membranes hepatic lipoproteins and bile. It is commonly used in cell signaling pathways. Phosphatidylethanolamine can prove helpful in treating Alzheimer. Brains affected by Alzheimer comprise fewer synapses and decreased levels of synaptic proteins, membrane phosphatides, choline and DHA. Phosphatidylethanolamine utilizes pyrimidine and a PUFA (for example, docosahexaenoic acid), which can significantly enhance levels of membrane phosphatide and synaptic protein in gerbil brains. Phosphatidylethanolamine also helps regulate homocysteine. It is synthesized by two pathways, CDP-choline pathway and methylation of phosphatidylethanolamine by phosphatidylethanolamine N-methyltransferase (PEMT). Recent research has suggested that PEMT is a significant consumer of methyl groups from S-adenosylmethionine (SAM) and plays an important role in determining homocysteine pools.

Potassium, a mineral that is quite common in our food. Potassium is needed for proper muscle growth, nervous system and brain function and to help balance the PH of our bodies.

Quercetin is a flavanoid derived from plants and is widely used as a nutritional supplement. There are many studies which are being conducted to exactly determine the benefits of Quercetin. It is said to have antioxidant and anti-inflammatory properties and hence is being tested to help curb and cure terminal diseases like cancer. The high intake of fruits and vegetables is good for cancer treatments. Many researchers believe that these qualities of Quercetin are what allow it to be used for treating cancer as well. Quercetin is classified into the IARC group 3; which categorizes food and drugs as that which are not carcinogenic.

Smilax- The genus Smilax includes approximately 300 different species of vines, found in warm regions like South America, North America and the Caribbean. Also known as Sarsaparilla, the roots of the plant are highly effective and thus used in various herbal treatments. For centuries, Smilax has been used by the natives for curing ailments and disorders like sexual impotence, dermatitis, syphilis to name just a few. The plant contains plant steroids called saponin as well as flavonoids. Theoretically, it is believed that the body synthesizes saponin into sex hormones, testosterone and estrogen. Since the plant has flavonoids, it also boasts of antioxidant properties. Smilax dietary supplements are extensively used for strength training and bodybuilding. The best benefit of using Smilax supplements is that there are absolutely no side effects.

Taraxacum Officinale, also called dandelion, has been traditionally used in herbal medicines. It can also be effective in treatment of kidney disorders, heartburn and indigestion. It can be beneficial in treating liver disease and can also be used in association with other medicines in treatment of upper respiratory tract infections, including bronchitis and pneumonia, and hepatitis. It is helpful in treatment of appetite loss and fluid retention. It is a good source of the nutrient lecithin that increases brain’s acetylcholine, a substance helpful in maintaining brain function and that can also be beneficial in slowing or even stopping progression of Alzheimer’s disease. Lecithin also helps the body maintain proper liver function.

Trimeylxanthine Anyhydrous is a form of caffeine that is found in many energy supplements. This stimulant is very beneficial for those who are looking to increase their energy and stamina levels. Trimelyxanthine anyhydrous is often combined with other ingredients to create various proprietary blends that are sold as weight loss supplements or energy supplements. Trimelyxanthine anyhydrous may also be marketed as a supplement that will bring about greater mental clarity, mental alertness, and focus. You can find this stimulant in both pill form and more potent powder form, although not generally sold alone but found as an active ingredient in other products.

Vinpocetine, a memory enhancer. Vinpocetine makes cerebral microcirculation (blood flow) easier, increases brain cell ATP production, and increases useability of glucose and oxygen.

Vitamin B3, commonly called Niacin, exists in two main forms, niacin and niacinamide. The niacin form produces a flushing and itching of the skin when taken at higher dosages and this feeling is only temporary.