Bioperine is derived from the extract of Piper nigrum L (black pepper) or Piper longum L (long pepper). Bioperine activates the thermogenesis process that generates energy at the cellular level. This process also helps in burning of fats. It also increases the absorption of nutrients and vitamins. It ensures that the body benefits and is able to efficiently use the nutrients from the food. It also boosts the metabolism that makes it effective in weight loss and maintenance. Because of the boost in metabolism, it also provides the body an increased supply of energy. It also aids in the proper digestion.

Citric Acid ~

Cyclic Adenosine Monophosphate 3'-5'-cyclic adenosine monophosphate or Cyclic Adenosine Monophosphate, a second messenger that mediates the action of several eptide or amine hormones, is abbreviated as cyclic AMP or cAMP. cAMP is thus vital for varied biological processes and used for intracellular signal transduction in various organisms. This major communicator is a result of the action of the enzyme adenyl cyclase on ATP. As such, cyclic AMP performs many physiological functions and is also responsible for increasing blood glucose levels. Adrenaline that enhances blood sugar levels in the body is able to do so by stimulating cAMP production. Cyclic AMP plays an important role in the following: urine regulation synthesis of flagellar proteins in bacteria hormone release sensory and nerve processes Apart from these functions, it also helps in breakdown of lipids in some organisms to produce energy in the absence of sufficient glucose.

Di-Sodium Phosphate is a white powder that is soluble in water and is highly hygroscopic. It is a phosphoric acid and is hence used commercially. It is wisely used as additive in anti-caking and is as well known as sodium hydrogen phosphate or disodium hydrogen orthophosphate. It is available in anhydrous and hydrated forms. Disodium phosphate is a significant ingredient of product package and can be used as cream of wheat so that the cooking time is quickened. Disodium phosphate is commonly used in the salt form. Disodium phosphate can be taken with large amounts of drinking water. However, nothing should be given orally to a person who is in the unconscious state. Disodium phosphate is not advisable for skin contact. The skin should be flushed immediately with lots of water for minimum 15 minutes. Thoroughly clean and acquire medical attention in case of development of any irritation. Medical attention is advised under any unusual circumstances.

Dioscorea Villosa extract is a medicinal herb commonly knows as the wild yam. It has medicinal properties that help in curing the pain caused during menstrual cycle, stomach cramps, and discomfort from gallstones and rheumatoid arthritis. It has been used fro centuries by the Native Americans. It is also used by herbalists for female and childbirth related problems. Along with herbal medicine, this plant is of great use in the modern medicine as well. It is because of this plant that birth control pills are so commonly and easily available. Its steroid like property explains the vast usage of this plant for medicinal purposes. But consumption of this extract may also lead to a number of side effects. Vomiting, diarrhea, nausea and headache are some of the most common side effects of dioscorea villosa extract.

Evodiamine, an alkaloid extract from the Evodiae Fructus plant is known as Evodiamine. It has been referred to as a “hot nature” herb in Chinese literature and medicine. Based on animal studies, Evodiamine increases the natural fat burning rate and stimulates vanilloids for reduction of fat intake. It increases body temperature, influences the adrenal glands to secrete catecholamines and also affects the metabolism of certain drugs. Since it acts like a thermogenic and increases the overall temperature, more fat and calories are burnt due to its intake. This alkaloidal compound has anti obesity effects due to UCP1 (uncoupling protein 1) thermogenesis. In part, evodiamine can prevent diet induced obesity from developing further. It is available in the form of supplement or through Evodiae Fructus plant.

Glabra, commonly known as licorice, is a root used to extract a sweet flavor from. Licorice is a plant belonging to the legume family, like peas and beans. It takes two to three years after planting for licorice to be harvested in autumn. It requires deep, fertile, well drained soil with a lot of sun to be able to grow. The extract from licorice is produced by boiling the roots with water and then evaporating all the water. This extract is then sold both in the form of solid and liquid. Glabra consists of a sweetener called glycyrrhizin which is many times sweeter than sucrose. It is used in lot cough syrups and in ayurvedic medicine. Candies made from licorice roots are famous all over the world. Hence it is in many pharmaceutical and confectionery products.

Guggulsterone- Commiphora wightii, or the so called Guggul tree is a flowering shrub or rather a small tree which can grow up to a size of 4 meters. Once very common in India, it is now there listed as endangered, but not in northern Africa or elsewhere in central Asia. It was very popular in the Indian Ayurvedic medicine, but also currently in the western medicine for treating of heart problems. The hydrocarbon secretion of Guggul contains a plant sterol, guggulsterone, which in the human body seems to act as an antagonist to the farnesoid X receptor. Furthermore, guggulsterone is active in increasing the natural thyroid production. This in turn stimulates the metabolism and may raise the body temperature, burning stored excess fat.

Horsetail Herb- Horsetail is a perennial herb that grows in sandy soil in the North America continent, Asia and Europe. Horsetail plants contain ancient lineage and are widely used in various roles. In the middle ages, the clumps of horsetail were employed as scouring pads that facilitates in iron cookware and hard pewter dishes cleaning. The horsetail has silicon content at highest levels and is significant in binding protein molecules as well as other connective tissues present in the human body. The horsetail properties as per clinical studies in Europe state that fractured or broken bones can be healed quicker if the patients take horsetail supplements. Horsetail reduces osteoporosis incidences and has health benefits linked. Athletes suffering from dislocated joints, sprains, torn ligament injuries can take advantage of getting cured by supplementing it with horsetail herb in their diet. The horsetail dosages are three tablets every day until it is completely healed. Bleeding problems can also be stopped if tea is consumed with this herb and similarly urinary problems can as well be treated.

L-Tyrosine is an amino acid taken to enhance the functions of the thyroid gland. It provides essential supplements to the body for fighting serious ailments. L-Tyrosine is a natural cure mainly for hypothyroidism and many other illnesses including protection of skin from the UV rays and depression. People suffering from hypothyroidism lack tyrosine and therefore do not respond to iodine supplements. Iodine supplements are of no use without tyrosine. Using L-tyrosine replaces vital amino acids which people having hypothyroidism lack. It produces thyroid hormones namely, norepinephrine, dopamine and epinephrine. L-tyrosine must be used by those who have a family history of under active thyroids and by those who have not got benefits from dieting efforts. L-tyrosine is taken in doses of 500mg 2 to 3 times everyday. People having high blood pressure must be cautious while taking this supplement.

Octopamine, which is a trace amine, recently believed to be a lipotropic for fat loss. Octopamine has low oral bioavailability and is readily broken down by MAOI, as well as metabolized by the gut wall, which may mean it would not work well when taken orally, but more research is needed to prove its positive or negative effects.

Phosphatidylcholine - Phosphatidylcholines are phospholipids which are found in all biological membranes. It is derived from egg yolk or soy beans. Found in abundant counts in lecithin, phosphatidylcholines are sometimes mistakenly referred to as lecithin. Phosphatidylcholine has been used in clinical emergencies, particularly in treatment of atheroma plaques in cardiac diseases. An interesting side effect has been observed during such use, namely that the injection area of phosphatidylcholine and deoxycholate displayed visible fat loss effects. There is currently widespread medical research in progress, in regards to injection lipolysis and the use of phosphatidylcholine for breaking down the fat cells and render the cosmetic procedure liposuction obsolete. While there are some side effects to this application, there were no long term damages noted, furthermore, the short term side effects were significantly less in comparison with the liposuction procedure.

Potassium is an electrolyte, a substance that maintains the fluid levels in the body. It is helpful in regulating blood pressure and heart function. Intake of potassium can benefit people suffering from hypertension. Research has found that a potassium supplement intake decreased incidence of stroke by 60 percent. It neutralizes acids and restores alkaline salts to bloodstream.  It acts along with sodium cells to maintain or restore membrane potentials. Potassium is also vital for nerve functioning and cardiovascular, and regulates nutrients’ transfer into cells and adds to muscle energy. It also helps recuperative powers, besides regulating water balance. Potassium is beneficial for eliminating wastes. It is helpful in controlling headaches and convulsions, and quickens healing of cuts, bruises and other injuries.

Quercetin is a flavanoid derived from plants and is widely used as a nutritional supplement. There are many studies which are being conducted to exactly determine the benefits of Quercetin. It is said to have antioxidant and anti-inflammatory properties and hence is being tested to help curb and cure terminal diseases like cancer. The high intake of fruits and vegetables is good for cancer treatments. Many researchers believe that these qualities of Quercetin are what allow it to be used for treating cancer as well. Quercetin is classified into the IARC group 3; which categorizes food and drugs as that which are not carcinogenic.

Smilax- The genus Smilax includes approximately 300 different species of vines, found in warm regions like South America, North America and the Caribbean. Also known as Sarsaparilla, the roots of the plant are highly effective and thus used in various herbal treatments. For centuries, Smilax has been used by the natives for curing ailments and disorders like sexual impotence, dermatitis, syphilis to name just a few. The plant contains plant steroids called saponin as well as flavonoids. Theoretically, it is believed that the body synthesizes saponin into sex hormones, testosterone and estrogen. Since the plant has flavonoids, it also boasts of antioxidant properties. Smilax dietary supplements are extensively used for strength training and bodybuilding. The best benefit of using Smilax supplements is that there are absolutely no side effects.

Taraxacum Officinale, also called dandelion, has been traditionally used in herbal medicines. It can also be effective in treatment of kidney disorders, heartburn and indigestion. It can be beneficial in treating liver disease and can also be used in association with other medicines in treatment of upper respiratory tract infections, including bronchitis and pneumonia, and hepatitis. It is helpful in treatment of appetite loss and fluid retention. It is a good source of the nutrient lecithin that increases brain’s acetylcholine, a substance helpful in maintaining brain function and that can also be beneficial in slowing or even stopping progression of Alzheimer’s disease. Lecithin also helps the body maintain proper liver function.

Trimeylxanthine Anyhydrous is a form of caffeine that is found in many energy supplements. This stimulant is very beneficial for those who are looking to increase their energy and stamina levels. Trimelyxanthine anyhydrous is often combined with other ingredients to create various proprietary blends that are sold as weight loss supplements or energy supplements. Trimelyxanthine anyhydrous may also be marketed as a supplement that will bring about greater mental clarity, mental alertness, and focus. You can find this stimulant in both pill form and more potent powder form, although not generally sold alone but found as an active ingredient in other products.

Vinpocetine is available in capsule form. Vinpocetine has certain properties which helps move the right amount of blood to the brain from the body. It also enhances certain components of the body. The advantage of consuming this natural substance is it helps oxygen and blood flow to the brain, this helps overcome obstacles which form in the eyes. Many diagnosed with eye disorders that have an impact on the overall eyesight have successfully recovered after using this natural extract. It eliminates cognitive impairments which cause low metabolism, dangerous clots and memory loss. Ingestion of Vinpocetine seems to have a positive correlation with the healing of Tinnitus – the buzzing or ringing sensation in the ear, which is mainly caused due to the disruption of natural blood flow through the entire body. It greatly helps optimize your overall health conditions. Vinpocetine mainly contains the extract from the popular periwinkle plant.

Vitamin B3 is also known as Niacin or nicotinic acid. It helps in the conversion of carbohydrates into glucose that serves as fuel for energy. It also helps the body in metabolizing fats and proteins. Niacin also helps in the production of hormones necessary for the body to function properly. It is also effective in improving the circulation in the body. It lowers cholesterol, triglycerides and blood sugar level. It also helps in the treatment of coronary artery disease. It also helps in regulating the blood sugar level. Niacin also helps prevent the Pellagra disease, which causes digestive problems, diarrhea, dermatitis, hyper-pigmentation, amnesia, dementia, delirium, and even death. Niacin also helps prevent Alzheimer’s disease, diabetes, and is also effective in treating acne.