Bioperine or black pepper, which is a common spice, has medicinal properties. It is a tropical plant and India is the largest producer of Piper Nigrum. It possesses anti-bacterial and anti-inflammatory properties. It acts as an antioxidant agent also. Black Pepper contains essential oil, which acts against intestinal flatulence and also stimulates sweating and urination. The essential oil found in Piper Nigrum stimulates stomach cells to produce HCl acid, which helps in digestion. Piper Nigrum also helps in absorption of certain essential micronutrients like coenzyme Q-10, beta-carotene and EGCG. Pepper has its contribution in Ayurvedic medicines also. Pepper seeds are used to prepare sinusitis relieving medicines. It also used for sore throat and dry cough.

Citric Acid ~

Cyclic Adenosine Monophosphate 3'-5'-cyclic adenosine monophosphate or Cyclic Adenosine Monophosphate, a second messenger that mediates the action of several eptide or amine hormones, is abbreviated as cyclic AMP or cAMP. cAMP is thus vital for varied biological processes and used for intracellular signal transduction in various organisms. This major communicator is a result of the action of the enzyme adenyl cyclase on ATP. As such, cyclic AMP performs many physiological functions and is also responsible for increasing blood glucose levels. Adrenaline that enhances blood sugar levels in the body is able to do so by stimulating cAMP production. Cyclic AMP plays an important role in the following: urine regulation synthesis of flagellar proteins in bacteria hormone release sensory and nerve processes Apart from these functions, it also helps in breakdown of lipids in some organisms to produce energy in the absence of sufficient glucose.

Di-Sodium Phosphate is a sodium salt of orthophosphoric acid and is used as an antioxidant synergist, stabiliser and buffering agent in food. It is also used as an emulsifier in the manufacture of pasteurised processed cheese.

Dioscorea Villosa extract is a medicinal herb commonly knows as the wild yam. It has medicinal properties that help in curing the pain caused during menstrual cycle, stomach cramps, and discomfort from gallstones and rheumatoid arthritis. It has been used fro centuries by the Native Americans. It is also used by herbalists for female and childbirth related problems. Along with herbal medicine, this plant is of great use in the modern medicine as well. It is because of this plant that birth control pills are so commonly and easily available. Its steroid like property explains the vast usage of this plant for medicinal purposes. But consumption of this extract may also lead to a number of side effects. Vomiting, diarrhea, nausea and headache are some of the most common side effects of dioscorea villosa extract.

Evodiamine- Tetradii Fructus, the fruit of the evodia plant, also known as Tetradium rutaecarpa, contains an active element that has recently been identified as evodiamine. This chemical compound is believed to be somewhat similar to capsaicin, the active compound found in the chili peppers. Some studies suggested that this vanilloid receptor agonist may interact with thermogenin, otherwise known as the uncoupling protein 1, UCP1, which is able to generate heat by a mechanism called thermogenesis. Tetradium rutaecarpa has been traditionally used in Chinese medicine for weight loss purposes and current studies seem to verify this information. Evodiamine has been embraced as a dietary supplement directed at weight loss, predominantly by the body building circles. This supplement is deemed to have energy burning and fat reducing, as well as diuretic properties.

Glabra, commonly known as licorice, is a root used to extract a sweet flavor from. Licorice is a plant belonging to the legume family, like peas and beans. It takes two to three years after planting for licorice to be harvested in autumn. It requires deep, fertile, well drained soil with a lot of sun to be able to grow. The extract from licorice is produced by boiling the roots with water and then evaporating all the water. This extract is then sold both in the form of solid and liquid. Glabra consists of a sweetener called glycyrrhizin which is many times sweeter than sucrose. It is used in lot cough syrups and in ayurvedic medicine. Candies made from licorice roots are famous all over the world. Hence it is in many pharmaceutical and confectionery products.

Guggulsterone is a plant sterol found in the resin of the guggul plant, Commiphora mukul. It acts as an antagonist of the farnesoid X receptor, which was earlier believed to result in decreased cholesterol synthesis in the liver.

Horsetail Herb- Horsetail products have been known to increase the production of urine. There is only a small amount of research in humans specifically using horsetail grass stem. Because there is a scientific basis for horsetail working as a diuretic, horsetail likely does increase urine. It is not clear what dose is safe or effective. One study suggests that horsetail may increase the rate of bone formation and aid in calcium deposition into bone. However, this study was limited.

L-Tyrosine is a proteinogenic polar amino acid, deemed not essential because it can be synthesized by the human body. As a member of the amino acid group that is being used by cells to build proteins, this building block derived its name from the Greek word tyros, which means cheese, because it was discovered in the cheese protein casein. L-Tyrosine can be synthesized from phenylalanine and can be found in foods high on protein, like soy products, poultry, cheese, bananas, dairy products and several seeds, including the sesame seeds. The unique phenol functionality and the occurrence in proteins that belong to the signal transduction process, make this amino acid different. Tyrosine can be converted by tyrosine hydroxylase enzyme into levodopa, a psychoactive drug that is used, among other uses, for clinical treatment of Parkinson’s disease. It is also involved in the synthesis of dopamine, norepinephrine and epinephrine.

Octopamine is related to noradrenaline. Octopamine was discovered by Vittorio Erspamer, an Italian scientist in 1948. Octopamine has a significant role in mollusks and is the central nervous system in snail. Octopamine also has a vital role in memory and learning in the fruit fly and honey bee. Octopamine is also useful for the firefly in releasing the light production. Octopamine mobilizes releasing fat in mammals and this has developed into promotion as a slimming aid on the internet. However, there is no apparent evidence about Octopamine facilitating weight loss. Octopamine also significantly increases the blood pressure in combination with stimulants such as weight loss supplements. This is extensively used in energy demanding insects such as spiders, lobsters, crabs and crayfish as their behaviors also include egg-laying, jumping and flying. Among vertebrates, Octopamine substitutes norepinephrine and as well exhibits common side effects. Octopamine is sited in the locust jump such that it modulates the muscle activity allowing the leg muscles to contract effectively.

Phosphatidylcholine has a role in membrane mediated cell signaling and is currently being experimented on weight loss treatments.

Potassium- Potassium is one of the essential minerals required for proper physiological functioning of the body. It plays an important role in the regulation of heart muscles. It helps to convert glucose to glycogen. Glycogen is essential for muscle formation. Potassium also helps to propagate nerve impulses by exchanging ion within cells and also helps in muscle contractions. It helps in balancing blood pressure. It controls the proper functioning of kidney. An average adult needs 3-5 gm of potassium daily. Due to deficiency of potassium, body observes tiredness. Other deficiency symptoms are weakness of muscles, low blood pressure, vomiting, poor kidney functions and Heart arrhythmias. Severe potassium shortages quickly direct to electrolyte disproportion which involves malfunctioning of nerves, kidney and heart.

Quercetin, a bioflavonoid derived mostly from blue-green algae. Quercetin is a strong antioxidant commonly found in onions, wine and tea.

Smilax is actually a genus that contains over three hundred species, mainly found in sub-tropical and tropical areas throughout the world. These are climbing plants, many of which have flowers and bear some kind of fruit. Many smilax plants have found uses in medicine, some for symptom remedy of the premenstrual syndrome; some others for treatments of hormonal imbalance induced or aggravated skin diseases. Many smilax plants are being used in local cuisines, either for herbal drinks or for sweet snacks; moreover, a Chinese variant has a long history as treatment against syphilis. Smilax officinalis has found use with body building circles as sarsaparilla root, where the plant’s sterols seem to influence human’s metabolic processes. The belief of many herbalists is that S. officinalis is making the body produce more testosterone.

Taraxacum Officinale, more commonly called Dandelion, is a bitter diuretic from the Asteraceae family of plants. It performs as a stimulant to the system, concentrated on the urinary organs. When combined with other medicinal herbal agents, it is useful in the treatment of liver and kidney disorders, gallbladder and urinary disorders, jaundice, constipation, cirrhosis, dyspepsia, weaknesses of the heart, eczema and chronic joint and skin problems. Dandelion is also a mild laxative and can be taken in large amounts because it is not poisonous. It promotes good digestion and also increases the appetite.

Trimeylxanthine Anyhydrous is a form of caffeine that is found in many energy supplements. This stimulant is very beneficial for those who are looking to increase their energy and stamina levels. Trimelyxanthine anyhydrous is often combined with other ingredients to create various proprietary blends that are sold as weight loss supplements or energy supplements. Trimelyxanthine anyhydrous may also be marketed as a supplement that will bring about greater mental clarity, mental alertness, and focus. You can find this stimulant in both pill form and more potent powder form, although not generally sold alone but found as an active ingredient in other products.

Vinpocetine is a derivitate of the periwinkle plant and was developed in the latter part of the 1960’s. It can be used as a dietary supplement, which can be found online.

Vitamin B3, also called Niacin, is a water-soluble vitamin needed for the conversion of food into energy so that it may be used by the body. Vitamin B3 also helps metabolize protein, sugar and fat.