Caffeine is a stimulant drug used for mental alertness and to accelerate energy and power. It is also used to delay muscle fatigue as it goes deep into the muscle tissues.

Cayenne, which contains Capsaicin, a thermogenic substance. A thermogenic raises your core temperature, which allows you to burn more calories from food, particularly when eating a high fat meal.

Hordenine, which is found in many grassy plants and grains. Hordenine is related to tyramine and may stimulate the release of norepinephrine to produce a stimulant effect.

PEA (Phenylethylamine) is a monoamine and alkaloid which functions as a trace amine, neurotransmitter or a neuromodulator. Phenylalanine, an amino acid, is the source from which phenethylamine, another name for PEA, is naturally biosynthesized through enzymatic decarboxylation. Compounds that are found in supplements in form of phenethylamines can be very diverse and include entactogens, anorectics, bronchodilators, hallucinogens, antidepressants and stimulants. Substituted phenethylamines are related to amphetamines, but also to dopamine, epinephrine, norepinephrine, phenylalanine and tyrosine. PEA is used by body builders and sportspeople mainly because of the stimulative effects as a neuromodulator, raising alertness, mood, concentration and focus. The additional stimulation of AMPA receptors, which boosts release of acetylcholine through the glutamatergic system, is an additional bonus of this popular supplement ingredient.